AI Method Reveals What Genomic Models Learn From DNA and Exposes Hidden Experimental Bias
Researchers at the Stowers Institute for Medical Research have built an interpretation method that shows, base by base, what a deep-learning model has learned from DNA, and used it to strip a hidden experimental bias out of genomic data. The method, called PISA, is described in a paper published in Nature Communications in August 2026 and announced by the institute on August 25, 2026. Sequence-to-function neural networks take raw DNA as input and predict the readout of genomics experiments… [...]
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